Patel, R., Garcia Romero, A., Bryant, A.S., Agak, G.W., and Hallem, E.A. (2025) Dopamine signaling drives skin invasion by human-infective nematodes. 
bioRxiv 2025.01.29.635547; doi: https://doi.org/10.1101/2025.01.29.635547.

Banerjee, N., Gang, S.S., Castelletto, M.L., Walsh, B., Ruiz, F., and Hallem, E.A. (2025) Carbon dioxide shapes parasite-host interactions in a human-infective nematode. Curr Biol 35: 277-286.e6. [PubMed]

Gregory, B.T., Desouky, M., Slaughter, J., Hallem, E.A., and Bryant, A.S. (2024) Thermosensory behaviors of the free-living life stages of Strongyloides species support parasitism in tropical environments. PLoS Negl Trop Dis 18: e0012529. [PubMed]

Castelletto, M.L., Akimori, D., Patel, R., Schroeder, N.E., and Hallem E.A. (2024) Introduction to Strongyloides stercoralis anatomy. J Nematol 56: 20240019. [PubMed]

Patel, R., Bryant, A.S., Castelletto, M.L., Walsh, B., Akimori, D., and Hallem, E.A. (2024) The generation of stable transgenic lines in the human-infective nematode Strongyloides stercoralis. G3 14: jkae122. [PubMed]

Moser, M.S. and Hallem, E.A. (2024) Astacin metalloproteases in human-parasitic nematodes. Adv Parasitol 126: 177-204. [PubMed]

Banerjee, N., Rojas Palato, E., Shih, P.-Y., Sternberg, P.W., and Hallem, E.A. (2024) Distinct neurogenetic mechanisms establish the same chemosensory valence state at different life stages in Caenorhabditis elegans. G3 14: jkad271. [PubMed]

McClure, C.R., Patel, R., and Hallem, E.A. (2023) Invade or die: behaviours and biochemical mechanisms that drive skin penetration in Strongyloides and other skin-penetrating nematodes. Phil Trans R Soc B 379: 20220434. [PubMed]

Bryant, A.S., Akimori, D., Stoltzfus, J.D.C., and Hallem, E.A. (2023) A standard workflow for community-driven manual curation of Strongyloides genome annotations. Phil Trans R Soc B 379: 20220443. [PubMed]

Al-Jawabreh, R., Anderson, R., Atkinson, L.E., Bickford-Smith, J., Bradbury, R.S., Breloer, M., Bryant, A.S., Buonfrate, D., Cadd, L.C., Crooks, B., Deiana, M., Grant, W., Hallem, E., Hedtke, S.M., Hunt, V., Khieu, V., Kikuchi, T., Kounosu, A., Lastik, D., van Lieshout, L., Liu, Y., McSorley, H.J., McVeigh, P., Mousley, A., Murcott, B., Nevin, W.D., Nosková, E., Pomari, E., Reynolds, K., Ross, K., STreit, A., Suleiman, M., Tiberti, N., and Viney, M. (2023) Strongyloides questions -- a research agenda for the future. Phil Trans R Soc B 379: 20230004. [PubMed]

Castelletto, M.L., Akimori, D., Patel, R., Schroeder, N.E. and Hallem, E.A. Introduction to Strongyloides stercoralis Anatomy. In WormAtlas, www.wormatlas.org. [WormAtlas]

Banerjee, N., Shih, P.Y., Rojas Palato, E.J., Sternberg, P.W., and Hallem, E.A. (2023) Differential processing of a chemosensory cue across life stages sharing the same valence state in Caenorhabditis elegans. Proc Natl Acad Sci USA 120: e2218023120. [PubMed]

Atkinson, L.E. and Hallem, E.A. (2022) Editorial – Strongyloides research in the post-genomics era. Mol Biochem Parasitol 252: 111522. [PubMed]

Wheeler,  N.J., Hallem, E.A., and Zamanian, M. (2022) Making sense of sensory behaviors in vector-borne helminths. Trends Parasitol 38: 841-853. [PubMed]

Mendez, P., Walsh, B., and Hallem, E.A. (2022) Using newly optimized genetic tools to probe Strongyloides sensory behaviors. Mol Biochem Parasitol 250: 111491. [PubMed]

Bryant, A.S., Ruiz, F., Lee, J., and Hallem, E.A. (2022) The neural basis of heat seeking in a human-infective parasitic worm. Curr Biol 32: 2206-2221. [PubMed]

Patel, R. and Hallem, E.A. (2022) Olfaction: one receptor drives opposite behaviors. Curr Biol 32:  R93-R96. [PubMed]

Castelletto, M.L., and Hallem, E.A. (2021) Generating transgenics and knockouts in Strongyloides species by microinjection. J Vis Exp 176: e63023, doi:10.3791/63023.

Chavez, I.N., Brown, T.M., Assié, A., Bryant, A.S., Samuel, B.S., and Hallem, E.A. (2021) Skin-penetrating nematodes exhibit life-stage-specific interactions with host-associated and environmental bacteria. BMC Biology 19: 221. [PubMed]

Carstensen, H.R., Villalon, R.M., Banerjee, N., Hallem, E.A., and Hong R.L. (2021) Steroid hormone pathways coordinate developmental diapause and olfactory remodeling in Pristionchus pacificus. Genetics 218: iyab071. [PubMed]

Bryant, A.S. and Hallem, E.A. (2021) The Wild Worm Codon Adapter: a web tool for automated codon adaptation of transgenes for expression in non-Caenorhabditis nematodes. G3 11: jkab146. [PubMed]
​
Bryant, A.S., DeMarco, S.F., and Hallem E.A. (2021) Strongyloides RNA-seq Browser: a web-based software platform for on-demand bioinformatics analyses of Strongyloides species. G3 11: jkab104. [PubMed]

Gang, S.S., Castelletto, M.L., Yang, E., Ruiz, F., Brown, T.M., Bryant, A.S., Grant, W.N., and Hallem, E.A. (2020) Chemosensory mechanisms of host seeking and infectivity in skin-penetrating nematodes. Proc Natl Acad Sci USA 117: 17913-17923. [PubMed]

Castelletto, M.L., Gang, S.S., and Hallem, E.A. (2020) Recent advances in functional genomics for parasitic nematodes. J Exp Biol 223:
jeb206482. [PubMed]

​Banerjee, N. and Hallem, E.A. (2020) Decoding inter-individual variability in experience-dependent behavioral plasticity. Neuron 105: 7-9. [PubMed]

Banerjee, N. and Hallem, E.A. (2020) The role of carbon dioxide in nematode behavior and physiology. Parasitology 147: 841-854. [PubMed]
​
Rengarajan, S., Yankura, K.A., Guillermin, M.L., Fung, W., and Hallem, E.A. (2019) Feeding state sculpts a circuit for sensory valence in Caenorhabditis elegans. Proc Natl Acad Sci USA 116: 1776-1781. [PubMed]

Bryant, A.S. and Hallem, E.A. (2018) Terror in the dirt: Sensory determinants of host seeking in soil-transmitted mammalian-parasitic nematodes. Int J Parasitol Drugs Drug Resist 8: 496-510. [PubMed]

Bryant, A.S. and Hallem, E.A. (2018) Temperature-dependent behaviors of parasitic helminths. Neurosci Lett 687: 290-303. [PubMed]

Bryant, A.S., Ruiz, F., Gang, S.S., Castelletto, M.L., Lopez, J.B., and Hallem, E.A. (2018) A critical role for thermosensation in host seeking by skin-penetrating nematodes. Curr Biol 28: 2338–2347. [PubMed]

Banerjee, N. and Hallem, E.A. (2018) Sexual dimorphisms: how sex-shared neurons generate sex-specific behaviors. Curr Biol 28: R254–R277. [PubMed]

Ruiz, F., Castelletto, M.L., Gang, S.S., and Hallem, E.A. (2017) Experience-dependent olfactory behaviors of the parasitic nematode Heligmosomoides polygyrus. PLoS Pathog 13: e1006709. [PubMed]

Gang, S.S., Castelletto, M.L., Bryant, A.S., Yang, E., Mancuso, N., Lopez, J.B., Pellegrini, M., and Hallem, E.A. (2017) Targeted mutagenesis in a human-parasitic nematode. PLoS Pathog 13: e1006675. [PubMed]

Guillermin, M.L., Carrillo, M.A., and Hallem, E.A. (2017) A single set of interneurons drives opposite behaviors in C. elegans. Curr Biol 27: 2630-2639. [PubMed]

Cevallos, J.A., Okubo, R.P., Perlman, S.J., and Hallem, E.A. (2017) Olfactory preferences of the parasitic nematode Howardula aoronymphium and its insect host Drosophila falleni. J Chem Ecol 43: 362-373. [PubMed]

Park, H.B., Sampathkumar, P., Perez, C.E., Lee, J.H., Tran, J., Bonanno, J.B., Hallem, E.A., Almo, S.C., and Crawford, J.M. (2017) Stilbene epoxidation and detoxification in a Photorhabdus luminescens-nematode symbiosis. J Biol Chem 292: 6680-6694. [PubMed]

Rengarajan, S., and Hallem, E.A. (2016) Olfactory circuits and behaviors of nematodes. Curr Opin Neurobiol 41: 136-148. [PubMed]

Gang, S.S. and Hallem, E.A. (2016) Mechanisms of host seeking by parasitic nematodes. Mol Biochem Parasitol 208: 23-32. [PubMed] 

Lee, J., Dillman, A.R., and Hallem, E.A. (2016) Temperature-dependent changes in the host-seeking behaviors of parasitic nematodes. BMC Biol 14: 36. [PubMed]

Peña, J.M., Carrillo, M.A., and Hallem, E.A. (2015) Variation in the susceptibility of Drosophila to different entomopathogenic nematodes. Infect Immun 83: 1130-1138. [PubMed]

Carrillo, M.A. and Hallem, E.A. (2015) Gas sensing in nematodes. Mol Neurobiol 51: 919-931. [PubMed]

Castelletto, M.L., Gang, S.S., Okubo, R.P., Tselikova, A.A., Nolan, T.J., Platzer, E.G., Lok, J.B., and Hallem, E.A. (2014) Diverse host-seeking behaviors of skin-penetrating nematodes. PLoS Pathog 10: e1004305. [PubMed]

Carrillo, M.A., Guillermin, M.L., Rengarajan, S., Okubo, R.P., and Hallem, E.A. (2013) O2-Sensing Neurons Control CO2 Response in C. elegans. J Neurosci 33: 9675-9683. [PubMed]

Chaisson, K.E., and Hallem, E.A. (2012) Chemosensory behaviors of parasites. Trends Parasitol 28: 427-436. [PubMed]

Dillman, A.R., Guillermin, M.L., Lee, J., Kim, B., Sternberg, P.W., and Hallem, E.A. (2012) Olfaction shapes host-parasite interactions in parasitic nematodes. Proc Natl Acad Sci USA 109: E2324-E2333. [PubMed]

Guillermin, M.L., Castelletto, M.L., and Hallem, E.A. (2011) Differentiation of carbon dioxide-sensing neurons in C. elegans requires the ETS-5 transcription factor. Genetics 189: 1327-1339. [PubMed]

Hallem, E.A., Dillman, D.R., Hong, A.V., Zhang, Y., Yano, J.M., DeMarco, S.F., and Sternberg, P.W. (2011) A sensory code for host seeking in parasitic nematodes. Curr Biol 21: 377-383. [PubMed]

Hallem, E.A., Spencer, W.C., McWhirter, R.D., Zeller, G., Henz, S.R., Rätsch, G., Miller, D.M. III, Horvitz, H.R., Sternberg, P.W., and Ringstad, N. (2011) Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans. Proc Natl Acad Sci USA 108: 254-259. [PubMed]

Hallem, E.A. and Sternberg, P.W. (2008) Acute carbon dioxide avoidance in C. elegans. Proc Natl Acad Sci USA 105: 8038-8043. [PubMed]

Hallem, E.A., Rengarajan, M., Ciche, T.A., and Sternberg, P.W. (2007) Nematodes, bacteria, and flies: a tripartite model for nematode parasitism. Curr Biol 17: 898-904. [PubMed]

Hallem, E.A. and Carlson, J.R. (2006) Coding of odors by a receptor repertoire. Cell 125: 143-160. [PubMed]

Hallem, E.A., Dahanukar, A., and Carlson, J.R. (2006) Insect odor and taste receptors. Ann Rev Entomol 51: 113-135. [PubMed]

Dahanukar, A., Hallem, E.A., and Carlson, J.R. (2005) Insect chemoreception.  Curr Opin Neurobiol 15: 423-430. [PubMed]

Hallem, E.A. and Carlson, J.R. (2004) The odor coding system of Drosophila. Trends Genet 20: 453-459. [PubMed]

Hallem, E.A. and Carlson, J.R. (2004) The spatial code for odors is changed by conditioning. Neuron 42: 359-361. [PubMed]

Hallem, E.A., Fox, A.N., Zwiebel, L.J., and Carlson, J.R. (2004) Olfaction: mosquito receptor for human-sweat odorant. Nature 427: 212-213. [PubMed]

Hallem, E.A., Ho, M.G., and Carlson, J.R. (2004) The molecular basis of odor coding in the Drosophila antenna. Cell 117: 965-979. [PubMed]

Shirke, S., Faber, S.C., Hallem, E., Makarenkova, H.P., Robinson, M.L., Overbeek, P.A., and Lang, R.A. (2001) Misexpression of IGF-I in the mouse lens expands the transitional zone and perturbs lens polarization. Mech Dev 101: 167-174. [PubMed]

Other Publications

Hallem, E.A. (2012) How do skin penetrating nematodes find your feet as you walk barefoot through soil? Invited blog post for Huffington Post Science, Dec. 4th, 2012. [article]